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Clusters of Characterized Proteins

Searching for EC 4.2.1.33 as complete word(s)

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Found 18 characterized proteins with matching descriptions. 14 of these are heteromeric.

Fetched 18 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 16 of these sequences

Found 3 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 424-509 amino acids (6/7 heteromeric)

P81291 isopropylmalate isomerase large subunit (EC 4.2.1.35) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
LEUC_METJA / P81291 Isopropylmalate/citramalate isomerase large subunit; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; EC 4.2.1.33; EC 4.2.1.35; EC 4.2.1.31 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
P81291 3-isopropylmalate dehydratase (EC 4.2.1.33); homoaconitate hydratase (EC 4.2.1.36) from Methanocaldococcus jannaschii
PFams: Aconitase, Aconitase
Heteromeric, 424 amino acids: PaperBLAST, CDD, Compare to cluster

P9WQF5 3-isopropylmalate dehydratase (EC 4.2.1.33) from Mycobacterium tuberculosis
PFams: Aconitase
473 amino acids: PaperBLAST, CDD, Compare to cluster

Q94AR8 isopropylmalate isomerase large subunit (EC 4.2.1.33) from Arabidopsis thaliana
LEUC_ARATH / Q94AR8 3-isopropylmalate dehydratase large subunit, chloroplastic; AtLEUC; Isopropylmalate isomerase large subunit 1; AtIIL1; IPMI LSU1; EC 4.2.1.33 from Arabidopsis thaliana (Mouse-ear cress)
Q94AR8 2-(omega-methylthio)alkylmalate dehydratase (subunit 2/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana
PFams: Aconitase
Heteromeric, 509 amino acids: PaperBLAST, CDD, Compare to cluster

b0072 3-isopropylmalate dehydratase subunit LeuC (EC 4.2.1.33) from Escherichia coli K-12 substr. MG1655
P0A6A6 3-isopropylmalate dehydratase subunit LeuC (EC 4.2.1.33) from Escherichia coli (strain K12)
ECOCYC|LEUC-MONOMER 3-isopropylmalate dehydratase large subunit; EC 4.2.1.33 from Escherichia coli K12
PFams: Aconitase
Heteromeric, 466 amino acids: PaperBLAST, CDD, Compare to cluster

LEUC1_SALTY / P15717 3-isopropylmalate dehydratase large subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aconitase
Heteromeric, 466 amino acids: PaperBLAST, CDD, Compare to cluster

LEUC_CORGL / P58946 3-isopropylmalate dehydratase large subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Aconitase
Heteromeric, 481 amino acids: PaperBLAST, CDD, Compare to cluster

LEUC_MYCBO / Q7TXH6 3-isopropylmalate dehydratase large subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
PFams: Aconitase
Heteromeric, 473 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 163-201 amino acids (4/5 heteromeric)

Q58673 isopropylmalate isomerase small subunit (EC 4.2.1.35) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
LEUD_METJA / Q58673 Isopropylmalate/citramalate isomerase small subunit; (R)-2-methylmalate dehydratase; (R)-citramalate dehydratase; 3-isopropylmalate dehydratase; Alpha-isopropylmalate dehydratase; Citraconate hydratase; Isopropylmalate isomerase; IPMI; Maleate hydratase; Malease; EC 4.2.1.33; EC 4.2.1.35; EC 4.2.1.31 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Q58673 3-isopropylmalate dehydratase (EC 4.2.1.33) from Methanocaldococcus jannaschii
PFams: Aconitase_C
Heteromeric, 168 amino acids: PaperBLAST, CDD, Compare to cluster

O59393 3-isopropylmalate dehydratase (EC 4.2.1.33) from Pyrococcus horikoshii
PFams: Aconitase_C
163 amino acids: PaperBLAST, CDD, Compare to cluster

LEUD1_SALTY / P04787 3-isopropylmalate dehydratase small subunit 1; Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1; EC 4.2.1.33 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aconitase_C
Heteromeric, 201 amino acids: PaperBLAST, CDD, Compare to cluster

LEUD_CORGL / Q8NQV7 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Aconitase_C
Heteromeric, 197 amino acids: PaperBLAST, CDD, Compare to cluster

b0071 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli K-12 substr. MG1655
P30126 3-isopropylmalate dehydratase subunit LeuD (EC 4.2.1.33) from Escherichia coli (strain K12)
PFams: Aconitase_C
Heteromeric, 201 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 251-256 amino acids (heteromeric)

LEUD2_ARATH / Q9LYT7 3-isopropylmalate dehydratase small subunit 3; AtLEUD2; Isopropylmalate isomerase 1; Isopropylmalate isomerase small subunit 3; IPMI SSU3; EC 4.2.1.33 from Arabidopsis thaliana (Mouse-ear cress)
Q9LYT7 2-(omega-methylthio)alkylmalate dehydratase (subunit 1/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana
PFams: Aconitase_C
Heteromeric, 253 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ZW84 isopropylmalate isomerase, small subunit (EC 4.2.1.170) from Arabidopsis thaliana
LEUD1_ARATH / Q9ZW84 3-isopropylmalate dehydratase small subunit 2; AtLEUD1; Isopropylmalate isomerase 2; Isopropylmalate isomerase small subunit 2; IPMI SSU2; EC 4.2.1.33 from Arabidopsis thaliana (Mouse-ear cress)
Q9ZW84 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana
PFams: Aconitase_C
Heteromeric, 256 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ZW85 isopropylmalate isomerase, small subunit (EC 4.2.1.33) from Arabidopsis thaliana
LEUD3_ARATH / Q9ZW85 3-isopropylmalate dehydratase small subunit 1; AtLEUD3; Isopropylmalate isomerase small subunit 1; IPMI SSU1; EC 4.2.1.33 from Arabidopsis thaliana (Mouse-ear cress)
Q9ZW85 2-(omega-methylthio)alkylmalate dehydratase (subunit 1/2) (EC 4.2.1.170); 3-isopropylmalate dehydratase (EC 4.2.1.33) from Arabidopsis thaliana
PFams: Aconitase_C
Heteromeric, 251 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (1/3 heteromeric)

LEUD_MYCBO / P65278 3-isopropylmalate dehydratase small subunit; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
P9WK95 3-isopropylmalate dehydratase (EC 4.2.1.33) from Mycobacterium tuberculosis
PFams: Aconitase_C
Heteromeric, 198 amino acids: PaperBLAST, CDD
(similar to SwissProt::P04787 from Cluster 2, but similarity to seed sequence is below thresholds)

LEUC_YEAST / P07264 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Aconitase, Aconitase_C
779 amino acids: PaperBLAST, CDD

GLOJ_GLAL2 / S3E7P8 3-isopropylmalate dehydratase large subunit gloJ; L-homotyrosine biosynthesis sub-cluster protein gloJ; Pneumocandin biosynthesis cluster protein J; EC 4.2.1.33 from Glarea lozoyensis (strain ATCC 20868 / MF5171)
PFams: Aconitase, Aconitase_C
880 amino acids: PaperBLAST, CDD